γδ T Cell Conference 2012

31.05.2012 13:45 - 14:00Welcome
 Chair: Paul Fisch and Wolfgang Schamel
 BeginTitleDuration
 13:45Welcome and Introduction15 min 

31.05.2012 14:00 - 15:15Mechanisms of ligand recognition (Session B)
 Chair: Marc Bonneville / Craig Morita
 BeginTitleDuration
 14:00γδ TCR recognition of Endothelial Protein C Receptor via an antibody-like binding mode within a multimolecular stress context15 min
B.E. Willcox (Birmingham Cancer Research UK Cancer Centre, School of Cancer Sciences, University of Birmingham, Birmingham, UK)
 14:15Key implication of CD277/Butyrophilin-3 (BTN3A) in cellular stress sensing by human Vγ9Vδ2 T cells15 min
E. Scotet (CNRS UMR 6299, Nantes, France)
 14:30Vγ9Vδ2 T cell activation correlates with CD277 membrane reorganization induced by isoprenoid pathway metabolites15 min
S. Nedellec (INSERM 892, Nantes, France)
 14:45Target specificity of an autoreactive human γδ T cell receptor in myositis15 min
J. Bruder (Department of Neuroimmunology Max-Planck-Institute of Neurobiology, Martinsried, Germany)
 15:00HLA B58 recognition by a human Vγ9/Vδ2 T-cell receptor15 min
A. Kaiser (Department of Pathology, Freiburg, Germany)

31.05.2012 15:15 - 16:15γδ T cell antigens (Session A)
 Chair: Erin Adams / Willi Born
 BeginTitleDuration
 15:15Cytomegalovirus and tumor stress surveillance by human Vδ1 γδ TCR binding to Ephrin Receptor A2 (EphA2)15 min
J. Dechanet-Merville (CNRS UMR 5164, Bordeaux Segalen University, Bordeaux, France)
 15:30Insulin B:9-23 peptide-reactive γδ T cells in the non-obese diabetic (NOD) mouse recognize an oxidized dimeric form of the peptide15 min
W.K. Born (National Jewish Health, Denver, USA)
 15:45Physiological autoreactivity of epidermal γδ TCRs15 min
T. Zal (University of Texas MD Anderson Cancer Center, Houston, USA)
 16:00γδ T cell recognition of CD1d/sulfatide in humans15 min
E. Adams (University of Chicago, Chicago, USA)

31.05.2012 16:15 - 17:15Coffee break / Poster session A, B
  
 BeginTitleDuration
 16:15Poster session A, B60 min 

31.05.2012 17:15 - 18:30Systems biology of T cell activation (TCRγδ vs. TCRαβ structure and activation) (Session C)
 Chair: Bruno Silva-Santos / Wolfgang Schamel
 BeginTitleDuration
 17:15Cohort analysis of human γδ T cell activation pathway using systems biology15 min
K. J. Puan (Singapore Immunology Network, Singapore, Singapore)
 17:30Computer simulation of γδ TCR clustering15 min
H. Kobayashi (Graduate School of Pharmaceutical Sciences, Chiba University, Japan)
 17:45Intravital and super-resolution microscopy of phosphotyrosine-rich assemblies located on projections (PALPs) in tissue-resident DETCs reveals immunological synapse-like structures15 min
G. Chodaczek (Department of Immunology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA)
 18:00Regulating γδ T cells: Skint1-mediated selection sets the TCR activation threshold15 min
G. Turchinovich (London Research Institute CRUK and Dept. of Immunobiology, KCL School of Medicine, London, UK)
 18:15The conformational change at CD3 modulates γδ T-cell signalling15 min
EP. Dopfer (Max Planck Institute of Immunobiology and Epigenetics and Institute of Biology III, Faculty of Biology, University of Freiburg, Germany)

31.05.2012 18:30 - 19:00Special presentation
  
 BeginTitleDuration
 18:30Differential effect on αβ versus γδ T cell development of a CD3ε mutant that prevents TCR from adopting the active conformation30 min
B. Alarcon (Centro de Biologia Molecular Severo Ochoa, CSIC-Universidad Autonoma de Madrid, Madrid, Spain)

31.05.2012 19:00 - 19:30Summary and general discussion
 Chair: Marc Bonneville / Willi Born / Adrian Hayday
 BeginTitleDuration
 19:00Summary and general discussion30 min 

01.06.2012 08:00 - 09:45γδ T cell development and homeostasis (Session D)
 Chair: Matthias Eberl / Julie Jameson
 BeginTitleDuration
 08:00Enforcement of the γδ T cell fate by the pre-TCR in DN3 cells with attenuated γδ-TCR signaling15 min
J.C. Zuniga-Pflucker (University of Toronto, Ontario, Canada)
 08:15IFN-gamma-secreting γδ T cells are generated by thymic ligand-independent signalling15 min
N. Sumaria (Blizard Institute, Barts and The London School of Medicine, Queen Mary University of London, United Kingdom)
 08:30IL-17 mediated negative feedback restricts development of IL-17 producing γδ T cells to an embryonic wave.15 min
J.D. Haas (Hannover Medical School, Hannover, Germany)
 08:45IL-17 producing γδ cells require TCR signaling for functional development15 min
M. Wencker (Peter Gorer Department of Immunobiology, King’s College London School of Medicine, London, UK)
 09:00Innate memory of human Vγ2Vδ2 T cells15 min
Craig T. Morita (Department of Internal Medicine, University of Iowa and the Veterans Affairs Health Care System, Iowa City, IA, USA)
 09:15Interleukin-7 selectively promotes mouse and human IL-17-producing γ/δ cells15 min
M.L. Michel (King’s College London, Guy’s Hospital, London, UK)
 09:30Intestinal crisis: γδ intraepithelial lymphocyte (IEL) decline in the obese intestine15 min
J. Jameson (The Scripps Research Institute, Dept. of Immunology and Microbial Sciences, La Jolla, United States)

01.06.2012 09:45 - 10:30Coffee break / Poster session D, E
  
 BeginTitleDuration
 09:45Poster session D, E45 min 

01.06.2012 10:30 - 12:30Phenotype and function of γδ T cells (Session E)
 Chair: Pablo Pereira / Emmanuel Scotet
 BeginTitleDuration
 10:30Antigen specific regulation of IgE antibodies by γδ T cells15 min
Y. Huang (Integrated Department of Immunology, National Jewish Health, Denver, CO 80206)
 10:45Human blood γδ T cells are reversibly licensed for professional antigen presentation following interaction with an opsonised target cell.15 min
J. Anderson (UCL Institute of CHild Health, London, UK)
 11:00UVB triggers NKG2D-ligand upregulation and γδ T cell activation by EGFR-mediated mRNA stabilization15 min
P. Vantourout (London Research Institute, Cancer Research UK, London, UK)
 11:15γδ T cells transdifferentiate towards αβ T cells15 min
K. Schilbach (Childrens Hospital, Dept. of Hematology and Oncology, University of Tübingen, Germany)
 11:30Developmental cues dictate interleukin-15 expression in γδ T cells15 min
SL. Colpitts (University of Connecticut Health Center, Farmington, CT, USA)
 11:45Differentiation of human peripheral blood Vδ1 T cells expressing Natural Cytotoxicity Receptors: implications for immunotherapies and the understanding of γδ T cell function15 min
K. Hudspeth (Laboratory of Clinical and Experimental Immunology, IRCCS, Istituto Clinico Humanitas, Rozzano, Milano, Italy)
 12:00Human fetal blood contains high levels of phosphoantigen-reactive effector-like Vγ9Vδ2 T cells15 min
D. Vermijlen (Institute for Medical Immunology, Université Libre de Bruxelles, Gosselies, Belgium, dvermijl@ulb.ac.be)
 12:15Human peripheral blood γδ T cells as harbingers of nitrogen-bisphosphonate induced immune dysfunction and osteonecrosis of the jaw15 min
S. Kalyan (Institute of Immunology, University Hospital Schleswig-Holstein, Kiel University, Kiel, Germany)

01.06.2012 12:30 - 13:15Lunch break / Posters can be viewed
  
 BeginTitleDuration
 12:30Posters can be viewed45 min 

01.06.2012 13:15 - 14:30 γδ T cells and their neighbours (Session F)
 Chair: Massimo Massaia / Wendy Havran
 BeginTitleDuration
 13:15A major regulatory role of local NKG2D ligand expression in transplantation15 min
V. Sofra (Immunosurveillance, Cancer Research, London, UK)
 13:30Co-ordinated crosstalk of human γδ T cells, neutrophils and monocytes in response to bacterial infections15 min
M. S. Davey (Cardiff Institute of infection and Immunity, School of Medicine, Cardiff University, United Kingdom)
 13:45Immunoparesis of bone marrow Vγ9Vδ2 T cells in human myeloma15 min
B. Castella (Department of Medicine and Experimental Oncology, Section of Hematology, University of Torino, Italy)
 14:00Knock out of HMBPP Synthase in recombinant Listeria vaccine vector led to a loss of the ability of the vaccine to induce Vγ2Vδ2 T-cell expansion and elicit Th17 and Th22 αβ T cell responses in macaques15 min
JT. Frencher (UIC College of Medicine, Chicago, USA)
 14:15γδ IEL migration is occludin-dependent and responsive to epithelial barrier loss15 min
K. Edelblum (The University of Chicago, Chicago, IL, USA)

01.06.2012 14:30 - 16:30γδ T cells in infectious diseaseses (Session G)
 Chair: Zheng Chen / Julie Déchanet-Merville
 BeginTitleDuration
 14:30Anti-parasitic γδ T cells are activated by secreted phoshoantigens15 min
C. Behr (CNRS UMR 5164, Bordeaux 2 University, Bordeaux, France)
 14:45CD3ε+ and CD3ε- Vδ1+ T cells from HIV-infected patients and healthy controls represent two distinct populations based on cell-surface phenotype and intracellular cytokine expression.15 min
P.J. Dunne (Human Cellular Immunology, Institute of Molecular Medicine, St. James’s Hospital and Trinity College Dublin, Dublin 8, Ireland)
 15:00Hallmarks of adaptive immunity in γδ T cells following oral Listeria infection15 min
L. Lefrançois (Center for Integrated Immunology and Vaccine Research, Department of Immunology, University of Connecticut Health Center, Farmington, Connecticut, USA)
 15:15Impacts of placental malaria on neonatal Vγ2Vδ2 T cells15 min
C. Cairo (Institute of Human Virology, University of Maryland Baltimore, Baltimore, US)
 15:30Implication of γδ T cells in the immune response against murine Cytomegalovirus15 min
J. Dechanet-Merville (CNRS UMR 5164, Bordeaux Segalen University, Bordeaux, France)
 15:45Protective role for Ag-specific Vγ2Vδ2 T effector cells in immunity against tuberculosis15 min
Z.W. Chen (University of Illinois College of Medicine, Chicago, USA)
 16:00Targeting human γδ-T cells: A potential novel strategy to treat human and avian influenza diseases15 min
W. Tu (University of Hong Kong)
 16:15γδ T cells protecting from MCMV infection15 min
M. Dietz (Institut für Klinische und Molekulare Virologie, Erlangen, Germany)

01.06.2012 16:30 - 17:00Coffee break / Poster session (Session F, G)
  
 BeginTitleDuration
 16:30Poster session F, G30 min 

01.06.2012 17:00 - 17:30Special presentation
  
 BeginTitleDuration
 17:00A modular in vivo system for T cell development30 min
T. Boehm (Max Planck Institute of Immunobiology and Epigenetics, Freiburg, Germany)

01.06.2012 17:30 - 18:00Summary, general discussion, and presentation of venues for the next conference
 Chair: Jean-Jacques Fournie / Wendy Havran / Miroslav Malkovsky
 BeginTitleDuration
 17:30Summary and general discussion15 min 
 17:45Presentations by candidates of the next γδ T-Cell Conference (maybe moved into the social event)15 min 

01.06.2012 19:00 - 23:00Social event "Spargelessen"
  
 BeginTitleDuration
 19:00The Bohrerhof "Asparagus farm"240 min 

02.06.2012 08:30 - 09:30γδ T cells in autoimmunity, tissue repair and inflamation (Session H)
 Chair: Ilan Bank / Rebecca O´Brien
 BeginTitleDuration
 08:30Blockage of IL-17 signaling and functional γδ T cell depletion improves clinical course of experimental biliary atresia15 min
C. Klemann (Centre for Paediatrics and Adolescent Medicine and Dept. of Pediatric Surgery, Hannover Medical School, Hannover, Germany)
 08:45γδ T cells prevent autoimmune αβ T cells from attacking the cornea15 min
R.L. O'Brien (National Jewish Health, Denver, Colorado, USA)
 09:00In situ activated IPP responsive synovial fluid Vγ9+ T cells in juvenile idiopathic arthritis release pro inflammatory cytokines and induce synovial fibroblast apoptosis15 min
V. Marcu-Malina (Laboratory of Immunoregulation, Sheba Medical Center, Tel Hashomer, Israel)
 09:15Rorγt+ innate lymphocytes and γδ T cells initiate psoriasiform plaque formation in mice15 min
S. Pantelyushin (Institute of Experimental Immunology, University of Zürich, Zürich, Switzerland)

02.06.2012 09:30 - 10:15Coffee break / Poster session H, I, J
  
 BeginTitleDuration
 09:30Poster session H, I, J45 min 

02.06.2012 10:15 - 10:30Results of the vote for the next conference
 Chair: Paul Fisch
 BeginTitleDuration
 10:15Results of the Vote15 min 

02.06.2012 10:30 - 12:30γδ T cells in malignancy (Session I)
 Chair: Shubhada Chiplunkar / Daniela Wesch
 BeginTitleDuration
 10:30Anti-lung cancer activity of ex vivo-expanded human γδ T cells and underlying molecular mechanisms15 min
L. Zhang (Toronto General Research Institute, University Health Network, Toronto, Canada)
 10:45γδ T cells could promote cancer progression of HPV-induced lesions15 min
D. Van hede (GIGA-I3/-Cancer, University of Liège, Liège, Belgium)
 11:00CD27 Expression Segregates Vδ2 γδ T-cell-mediated Cytotoxicity against Acute Myeloid Leukemia Cell Lines15 min
C. Allen (Institute of Medical Science, University of Toronto, Toronto, Canada)
 11:15CMV-Independent Lysis of Glioma-derived Cell Lines and Primary Tumor Explants by in vitro Expanded/Activated Vδ1+ γδ T Cells15 min
A. Knight (The Department of Haematology, University College London, Rowland Hill Street, London, NW3 2PF, United Kingdom)
 11:30Circulating γδ T cells are activated and expanded against high-grade gliomas15 min
L. Lamb (University of Alabama at Birmingham, Birmingham, USA)
 11:45Dysfunctional Vγ9Vδ2 T cells are associated with increased mevalonate pathway activity in tumor cells and negative predictors of time to first treatment in chronic lymphocytic leukemia (CLL)15 min
C. Vitale (Laboratorio di Ematologia Oncologica, Centro di Ricerca in Medicina Sperimentale, Torino, Italy)
 12:00Involvement of notch signaling in activation of human γδ T cells and anti tumor immunity15 min
S. Chiplunkar (Tata Memorial Centre, Kharghar, Navi Mumbai, India)
 12:15The pro-inflammatory CCL2/ CCR2 pathway determines tumor infiltration by γδ T cells15 min
T. Lança (Instituto de Medicina Molecular, Lisboa, Portugal)

02.06.2012 12:30 - 13:00Lunch break
  
 BeginTitleDuration
 12:30Lunch break30 min 

02.06.2012 13:00 - 14:45γδ T cells in therapy (Session J)
 Chair: Rupert Handgretinger / Richard Lopez
 BeginTitleDuration
 13:00Adoptive immunotherapy of glioblastoma multiforme using γδ T cells.15 min
V. Marcu-Malina (Laboratory of Immunoregulation, Sheba Medical Center, Tel Hashomer, Israel)
 13:15Interferon-α therapy alters peripheral γδ T cell compartments in Chronic Myeloid Leukemia patients15 min
G.M. Siegers (Imaging Research Laboratories, Robarts Research Institute, Western University, London, Ontario, Canada)
 13:30Rapid immune recovery of γδ+ and αβ+ T- lymphocytes and NK cells after haploidentical transplantation of TcRαβ/CD19-depleted peripheral stem cells.15 min
R. Handgretinger (Children’s University Hospital, Tübingen, Germany)
 13:45Bispecific antibodies Her2xCD3 and Her2xCD16 enhanced lysis of pancreatic ductal adenocarcinoma by γδ T cells.15 min
D. Wesch (Institute of Immunology, Christian-Albrechts University Kiel, Kiel, Germany)
 14:00Exploiting allogeneic γδ T cells for the immunotherapy of malignant diseases15 min
R. Lopez (University of Alabama at Birmingham, Birmingham, Alabama, USA)
 14:15Multipotent Vδ2-negative γδ T-cells after CMV-reactivation in allogeneic stem cell transplantation15 min
W. Scheper (Dept. of Hematology, University Medical Center Utrecht, Utrecht, The Netherlands)
 14:30γ9- and δ2-CDR3 domains regulate functional avidity of T cells harbouring γ9δ2 T cell receptors15 min
C. Grunder (Dept. of Hematology and Immunology, UMC Utrecht, Utrecht, The Netherlands)

02.06.2012 14:45 - 14:45Closure of meeting, Farewall
 Chair: Paul Fisch and Wolfgang Schamel
  Title 

31.05.2012 16:15Poster session A: γδ T cell antigens
  
  Title 
  HLA-I molecules as target of Vδ3 TCR in tumour B cells 
R. Marlin (CNRS UMR 5164, Bordeaux 2 University, Bordeaux, France)
  Novel phosphoantigens for human Vγ2Vδ2 T cells produced by Staphylococcus aureus and Streptococcus Gram-positive cocci using the mevalonate isoprenoid pathway 
Craig T. Morita (Department of Internal Medicine, University of Iowa and the Veterans Affairs Health Care System, Iowa City, IA, USA)

31.05.2012 16:15Poster session B: Mechanisms of ligand recognition
  
  Title 
  Vγ9Vδ2 T-cell proliferation driven by soluble isopentenyl-pyrosphosphate (IPP) released by dendritic cells (DC) treated with zoledronic acid. 
P. Sciancalepore (Divisione di Ematologia dell’Università di Torino, Torino, Italy)

01.06.2012 09:45Poster session D: γδ T cell development and homeostasis
  
  Title 
  Depletion of epidermal Wnt secretion causes psoriasis-like skin lesions 
Iris. Augustin (Division of Signaling and Functional Genomics, DKFZ, Heidelberg)
  Evolution of Antigen Recognition by Vγ9Vδ2 T cells 
M.M. Karunakaran (Institute for Virology and Immunobiology, University of Wuerzburg, Wuerzburg, Germany)
  Impact of γδ T cells on murine intestinal mucus properties 
O. Kober (Institute of Food Research, Norwich NR4 7UA, UK)
  Influence of thymic localisation of γδ T cells on their differentiation and peripheral homeostasis of IL-17A+ γδ T cells 
A. Reinhardt (Institute of Immunology, Hannover Medical School, Hannover, Germany)
  Intrathymic programming of murine γδ T cells by Notch signaling 
K. Shibata (Medical Institute of Bioregulation, Kyushu University, Japan)
  Transcriptional and epigenetic mechanisms of differentiation of pro-inflammatory γδ T cell subsets 
Karine. Serre (Instituto de Medicina Molecular, Lisboa, Portugal)

01.06.2012 09:45Poster session E: Phenotype and function of γδ T cells
  
  Title 
  Bisphosphonate-related osteonecrosis of the jaw: An immunological perspective 
P. Ryan (Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK)
  CD28 costimulation controls the survival and proliferation of murine and human γδ T cells via interleukin-2 production 
J.C. Ribot (Instituto de Medicina Molecular, Lisboa, Portugal)
  Crosstalk of γδ T cells and monocytes triggers the acute phase reaction upon intravenous administration of aminobisphophonates 
JL. Welton (Institute of Infection and Immunity, School of Medicine, Cardiff University, Cardiff)
  Enhancement of expansion of γδ T cells by CD56brightCD11c+ cells induced by IL-2/IL-18 
W. Li (Hyogo College of Medicine, Nishinomiya, Japan)
  High-throughput sequencing of γδ TCR 
E. Kashani (Hannover Medical School, Hannover, Germany)
  Phenotype and Functional Characterization of Expanded γδ T Cells 
M.W.A. Khan (Institute of Infection and Immunity, School of Medicine, Cardiff University CF14 4XN, Cardiff, Wales, United Kingdom)
  Phenotypic and functional characterisation of porcine γδ T-cells 
C. Sedlak (Institute of Immunology, Department of Pathobiology, University of Veterinary Medicine, Vienna, Austria)
  Role of microRNAs in the differentiation of pro-inflammatory γδ T cell subsets 
N. Schmolka (Instituto de Medicina Molecular, Faculdade de Medicina, Universidade de Lisboa, Portugal)
  Role of mTOR in γδ T cell cytokine production and function 
Z. Yin (College of Life Sciences, Nankai University, Tianjin 300071, China)

01.06.2012 16:30Poster session F: γδ T cells and their neighbours
  
  Title 
  A critical role for the γδ TCR in dendritic epidermal T cell (DETC) function 
O. Sobolev (Cancer Research UK, London, United Kingdom)
  A regulatory crosstalk between γδ T cells and mesothelial cells 
CY. Lin (Department of Nephrology, Taoyuan, Taiwan)
  Defining novel afferent signals in the lymphoid stress surveillance response 
B. Hunt (Peter Gorer Department of Immunobiology, King’s College London School of Medicine at Guy’s Hospital, London, UK)
  Lymphoid stress-surveillance by γδ T cells – linking tumour immune-surveillance and atopy 
J. Strid (Peter Gorer Department of Immunobiology, King’s College School of Medicine at Guy’s Hospital, London SE1 9RT, UK)
  PD-1 and CTLA-4 contribute to Vδ2Vγ9 T cell-mediated suppression. 
C. Peters (Institute of Immunology, Christian-Albrechts-University, Kiel, Germany)
  The impact of Skint genes on peripheral γδ T cell function 
R. Hart (Cancer Research UK, London, UK)
  The interaction between intestinal epithelial lymphocytes and epithelial cells in allergic sensitization to food proteins 
Marianne. Bol-Schoenmakers (Institute for Risk Assessment Sciences, Utrecht University, Utrecht, The Netherlands)
  Thymic programming and effector properties of human innate lymphocytes 
E. Tolosa (Institute of Immunology, UKE, Hamburg, Germany)
  Vγ9Vδ2 T cells induce maturation of dendritic cells but not B cells into antigen-presenting cells 
A. Petrasca (Discipline of Immunology, School of Medicine)

01.06.2012 16:30Poster session G: γδ T cells in Infectious diseaseses
  
  Title 
  Human γδ T cells in severe bacterial sepsis and clinical outcomes 
M. Morgan (Institute of infection and immunity, Cardiff University, United Kingdom)
  Intestinal γδ intra epithelial lymphocytes: a local modulator of gut barrier functions 
I. Hautefort (Integrated Biology of the Gastrointestinal Tract Research Programme, Institute of Food Research, Norwich, United Kingdom)
  Role of IL-17 producing γδ T-cells in microbial infections 
I. Sandrock (Institute of Immunology, Hannover Medical School, Hannover, Germany)
  The phosphoantigen-expanded human γδ-T cells show potent antiviral activity against EBV infection 
Zheng. Xiang (Departments of Paediatrics and Adolescent Medicine1, Li Ka Shing Faculty of Medicine, University of Hong Kong, Hong Kong SAR, China)
  Unexpected pathogenic role of γδ T lymphocytes in cerebral malaria following infection with Plasmodium sporozoites 
R. Neres (Instituto de Medicina Molecular, Faculdade de Medicina, University of Lisbon, Lisbon, Portugal)
  γδ T cells as a novel cell effector in the antibody mediated kidney allograft rejection 
J. Dechanet-Merville (CNRS UMR 5164, Bordeaux Segalen University, Bordeaux, France)
  Role of γδ-T cells in susceptibility to experimental cerebral malaria 
R.D. Lopez (University of Alabama at Birmingham, Birmingham, Alabama, USA)

02.06.2012 09:30Poster session H: γδ T cells in autoimmunity, tissue repair and inflamation
  
  Title 
  Activated γδ T cells inhibit osteoclast differentiation and resorptive activity in vitro 
A. Pappalardo (University of Aberdeen, Aberdeen, United Kingdom)
  Can γδ T cells mediate acute interstital nephritis? 
M. Noriega (Molecular Pathology,Department of Pathology, Freiburg, Germany)
  Elucidating the role of γδ T cell subsets in coeliac disease 
M. Dunne (National Children's Research Centre, Dublin, Ireland)
  γδ T cells and their role in rheumatic diseases during pregnancy 
M. Tham (Department of Rheumatology, Clinical Immunology and Allergology, Inselspital, University of Bern, Switzerland)
  γδ t cells in Granulomatosis with Polyangiitis 
J. Fazio (Institute of Immunology, UKSH, Kiel, Germany)

02.06.2012 09:30Poster session I: γδ T cells in malignancy
  
  Title 
  Effects of concomitant therapies on γδ T cell responses to zoledronate in patients with advanced malignancy 
D. Enting (London Research Institute CRUK and Dept. of Immunobiology, KCL School of Medicine, London, UK)
  Genomic and functional studies in T-cell Acute Lmphoblastic Leukemia patients exhibiting clonal T Cell Receptor γ and δ gene rearrangement 
J. Bhat (Advanced Centre for Treatment Research & Education in Cancer, Kharghar, Navi Mumbai-410 210, India)
  Inhibition of NKG2D ligand shedding on tumor cells increases their susceptibility to γδ T cell-mediated killing in vitro 
G. Chitadze (Institute of Immunology, University of Kiel, Germany)
  Understanding the dual role of murine γδ T cells in tumour surveillance and tumour progression 
M. Rei (GABBA, Porto, Portugal)
  Zoledronic Acid-Induced Expansion of Vγ2Vδ2 T Cells from Early-Stage Breast Cancer Patients: Effect of IL-18 on Helper NK Cells 
Y. Tanaka (Kyoto University, Kyoto, Japan)

02.06.2012 09:30Poster session J: γδ T cells in therapy
  
  Title 
  Analysis of absolute cell numbers and cytotoxic function of Vδ2-bearing γδ T cells in patients with pancreatic ductal adenocarcinoma 
S. Adam-Klages (Institute of Immunology, Christian-Albrechts-University Kiel, Germany)
  Cytotoxicity of freshly isolated γδ T cells is induced by bispecific antibody Her2xCD3 alone 
H.H. Oberg (Institute of Immunology, Christian-Albrechts-University, Kiel, Germany)
  Extensive expansion of primary human γδ T cells generates cytotoxic effector memory cells that can be labeled with Feraheme for cellular MRI 
G.M. Siegers (Imaging Research Laboratories, Robarts Research Institute, Western University, London, Ontario, Canada)
  Sensitization of breast cancer cells to γδ T cell-mediated cytotoxicity by suppression of the apoptosis inhibitor c-FLIP 
H-C. Chen (Cardiff Institute of Infection and Immunity, School of Medicine, Cardiff University, Cardiff, UK)
  Tumor targeting using a soluble γδ T-cell receptor–FasL chimeric protein 
J. Dechanet-Merville (CNRS UMR 5164, Bordeaux Segalen University, Bordeaux, France)
  γδ T cells and their controversial role in GvHD 
K. Thamm (Institute of Immunology, Hannover, Germany)
  Human Vδ1 γδ T cells exert potent specific cytotoxicity against primary multiple myeloma cells 
A. Knight (Department of Haematology, Royal Free Hospital, University College Medical School London, United Kingdom)